WHY MONODISPERSE PARTICLES GIVE BETTER PACKED BEDS
– MORE UNIFORM FLOW PATHS
– MORE REPRODUCIBLE BED COMPRESSION
– BETTER RADIAL HOMGENEITY
– REDUCED PACKING HETEROGENEITY
Uniform interstitial spaces create consistent solvent velocity and minimise preferential channels and Eddy diffusion – reducing the A-term in the Van Deemter equation.
More uniform local density and permeability throughout the bed. Fewer stagnant zones and microchannels leading to narrower peaks and higher plate count.
More consistent particle arrangement at the column wall reduces wall effects and radial velocity gradients – critical in narrow bore and UHPLC columns.
Particles settle and compress uniformly during packing due to absence of differing sedimentation rates. Minimises segregation, inlet voids and axial density gradients.
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